A database of hormones and their receptors |
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HMRbase accession number | 10194 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Corticotropin |
Mature Hormone Sequence | SYSMEHFRWGKPVGRKRRPVKVYPNGVEEESAEAYPTEM |
Position of mature hormone in Pre-Hormone protein | 39 Residues from position (135-173) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10195 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Melanotropin alpha (Alpha-MSH) |
Mature Hormone Sequence | SYSMEHFRWGKPV |
Position of mature hormone in Pre-Hormone protein | 13 Residues from position (135-147) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10196 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Melanotropin beta (Beta-MSH) |
Mature Hormone Sequence | DGSYKMHHFRWSRPPKD |
Position of mature hormone in Pre-Hormone protein | 17 Residues from position (207-223) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10197 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Beta-endorphin |
Mature Hormone Sequence | YGGFMKSWDERSQKPLLTLFKNVIIKDGHQKKGQ |
Position of mature hormone in Pre-Hormone protein | 34 Residues from position (226-259) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10198 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Met-enkephalin |
Mature Hormone Sequence | YGGFM |
Position of mature hormone in Pre-Hormone protein | 5 Residues from position (226-230) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10745 |
Swiss-prot Accession number | P79885 (Sequence in FASTA format) |
Description | Somatotropin precursor (Growth hormone). |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | Secreted protein |
Developmental Stage | N/A |
Similarity | Belongs to the somatotropin/prolactin family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation |
Protein Length | 211 Amino acids |
Molecular weight | 23999 |
References | 1 PubMed abstract 8672235 |
Domain Name | Hormone_1 |
Hormone Name | Somatotropin |
Mature Hormone Sequence | AFPLYSLFTNAVIRAQHLHQLAADIYKDFERTYVPEEQRQSSKSSPSAICYSESIPAPTGKDEAQQRSDVELLRFSLALIQSWISPLQTLSRVFSNSLVFGTSDRIFEKLQDLERGIVTLTREIDEGSPRIAAFLTLTYEKFDTNLRNDDALMKNYGLLACFKKDMHKVETYLKVMKCRRFVESNCTL |
Position of mature hormone in Pre-Hormone protein | 188 Residues from position (24-211) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |
HMRbase accession number | 10927 |
Swiss-prot Accession number | Q91082 (Sequence in FASTA format) |
Description | Corticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin]. |
Source organism | Lepisosteus osseus (Long-nosed gar) |
Taxonomical Classification | Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the POMC family. |
Tissue Specificity | N/A |
Post translational modification | Specific enzymatic cleavages at paired basic residues yield the different active peptides. |
Function | Precursor protein for pituitary hormones that regulate stress and environmental adaptation |
Protein Length | 259 Amino acids |
Molecular weight | 29675 |
References | 1 PubMed abstract 9268621 2 PubMed abstract 9268621 |
Domain Name | NPP ACTH_domain Op_neuropeptide |
Hormone Name | Gamma-melanotropin-like segment |
Mature Hormone Sequence | NYAKSHFRSTALGRRTNGSVGSS |
Position of mature hormone in Pre-Hormone protein | 23 Residues from position (72-94) |
Receptor | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Receptor for this Hormone are either unknown or have not yet been curated |