A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10194
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameCorticotropin
Mature Hormone SequenceSYSMEHFRWGKPVGRKRRPVKVYPNGVEEESAEAYPTEM
Position of mature hormone in Pre-Hormone protein39 Residues from position (135-173)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10195
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin alpha (Alpha-MSH)
Mature Hormone SequenceSYSMEHFRWGKPV
Position of mature hormone in Pre-Hormone protein13 Residues from position (135-147)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10196
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin beta (Beta-MSH)
Mature Hormone SequenceDGSYKMHHFRWSRPPKD
Position of mature hormone in Pre-Hormone protein17 Residues from position (207-223)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10197
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameBeta-endorphin
Mature Hormone SequenceYGGFMKSWDERSQKPLLTLFKNVIIKDGHQKKGQ
Position of mature hormone in Pre-Hormone protein34 Residues from position (226-259)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10198
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMet-enkephalin
Mature Hormone SequenceYGGFM
Position of mature hormone in Pre-Hormone protein5 Residues from position (226-230)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10745
Swiss-prot Accession numberP79885 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation
Protein Length211 Amino acids
Molecular weight23999
References1  PubMed abstract 8672235
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceAFPLYSLFTNAVIRAQHLHQLAADIYKDFERTYVPEEQRQSSKSSPSAICYSESIPAPTGKDEAQQRSDVELLRFSLALIQSWISPLQTLSRVFSNSLVFGTSDRIFEKLQDLERGIVTLTREIDEGSPRIAAFLTLTYEKFDTNLRNDDALMKNYGLLACFKKDMHKVETYLKVMKCRRFVESNCTL
Position of mature hormone in Pre-Hormone protein188 Residues from position (24-211)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10927
Swiss-prot Accession numberQ91082 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Gamma-melanotropin-like segment; Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Melanotropin beta(Beta-MSH); Beta-endorphin; Met-enkephalin].
Source organismLepisosteus osseus (Long-nosed gar)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Semionotiformes; Lepisosteidae;Lepisosteus.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionPrecursor protein for pituitary hormones that regulate stress and environmental adaptation
Protein Length259 Amino acids
Molecular weight29675
References1  PubMed abstract 9268621
2  PubMed abstract 9268621
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameGamma-melanotropin-like segment
Mature Hormone SequenceNYAKSHFRSTALGRRTNGSVGSS
Position of mature hormone in Pre-Hormone protein23 Residues from position (72-94)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated